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Discovery of a previously unknown biosynthetic capacity of naringenin chalcone synthase by heterologous expression of a tomato gene cluster in yeast

Chalcone synthase (CHS) canonically catalyzes carbon-carbon bond formation through iterative decarboxylative Claisen condensation. Here, we characterize a previously unidentified biosynthetic capability of SlCHS to catalyze nitrogen-carbon bond formation, leading to the production of a hydroxycinnam...

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Bibliografiset tiedot
Julkaisussa:Sci Adv
Päätekijät: Kong, Deze, Li, Sijin, Smolke, Christina D.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Association for the Advancement of Science 2020
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7608815/
https://ncbi.nlm.nih.gov/pubmed/33127687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.abd1143
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