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ERK phosphorylates chromosomal axis component HORMA domain protein HTP-1 to regulate oocyte numbers

Oocyte numbers, a critical determinant of female reproductive fitness, are highly regulated, yet the mechanisms underlying this regulation remain largely undefined. In the Caenorhabditis elegans gonad, RAS/extracellular signal–regulated kinase (ERK) signaling regulates oocyte numbers; mechanisms are...

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Dades bibliogràfiques
Publicat a:Sci Adv
Autors principals: Das, Debabrata, Chen, Shin-Yu, Arur, Swathi
Format: Artigo
Idioma:Inglês
Publicat: American Association for the Advancement of Science 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7608811/
https://ncbi.nlm.nih.gov/pubmed/33127680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.abc5580
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