A Requirement for ERK dependent Dicer Phosphorylation in Coordinating Oocyte-to-Embryo Transition in Caenorhabditis elegans

Signaling pathways and small RNAs direct diverse cellular events, but few examples are known of defined signaling pathways directly regulating small RNA biogenesis. We show that ERK phosphorylates Dicer on two conserved residues in its RNAse IIIb and dsRNA-binding domain, and phosphorylation of thes...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Dev Cell
Egile Nagusiak: Drake, Melanie, Furuta, Tokiko, Man, Kin Suen, Gonzalez, Gabriel, Liu, Bin, Kalia, Awdhesh, Ladbury, John, Fire, Andrew Z., Skeath, James B, Arur, Swathi
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2014
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4261158/
https://ncbi.nlm.nih.gov/pubmed/25490268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2014.11.004
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