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Spatial and Temporal Analysis of Active ERK in the C. elegans Germline

The evolutionarily conserved extracellular signal transducing RTK-RAS-ERK pathway is an important kinase-signaling cascade that controls multiple cellular and developmental processes principally via activation of ERK, the terminal kinase of the pathway. Tight regulation of ERK activity is essential...

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Bibliographic Details
Published in:J Vis Exp
Main Authors: Gervaise, Amanda L., Arur, Swathi
Format: Artigo
Language:Inglês
Published: MyJove Corporation 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5226324/
https://ncbi.nlm.nih.gov/pubmed/27929466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/54901
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