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The interaction of DNA repair factors ASCC2 and ASCC3 is affected by somatic cancer mutations
The ASCC3 subunit of the activating signal co-integrator complex is a dual-cassette Ski2-like nucleic acid helicase that provides single-stranded DNA for alkylation damage repair by the α-ketoglutarate-dependent dioxygenase AlkBH3. Other ASCC components integrate ASCC3/AlkBH3 into a complex DNA repa...
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| Publicado no: | Nat Commun |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7608686/ https://ncbi.nlm.nih.gov/pubmed/33139697 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-19221-x |
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