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A Snu114–GTP–Prp8 module forms a relay station for efficient splicing in yeast

The single G protein of the spliceosome, Snu114, has been proposed to facilitate splicing as a molecular motor or as a regulatory G protein. However, available structures of spliceosomal complexes show Snu114 in the same GTP-bound state, and presently no Snu114 GTPase-regulatory protein is known. We...

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Bibliografiset tiedot
Julkaisussa:Nucleic Acids Res
Päätekijät: Jia, Junqiao, Ganichkin, Oleg M, Preußner, Marco, Absmeier, Eva, Alings, Claudia, Loll, Bernhard, Heyd, Florian, Wahl, Markus C
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Oxford University Press 2020
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7192624/
https://ncbi.nlm.nih.gov/pubmed/32196113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa182
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