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Mutagenesis of Snu114 domain IV identifies a developmental role in meiotic splicing
Snu114, a component of the U5 snRNP, plays a key role in activation of the spliceosome. It controls the action of Brr2, an RNA-stimulated ATPase/RNA helicase that disrupts U4/U6 snRNA base-pairing prior to formation of the spliceosome’s catalytic centre. Snu114 has a highly conserved domain structur...
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| Publicado no: | RNA Biol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6380292/ https://ncbi.nlm.nih.gov/pubmed/30672374 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15476286.2018.1561145 |
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