Analysis of brain networks and fecal metabolites reveals brain–gut alterations in premenopausal females with irritable bowel syndrome

Alterations in brain–gut–microbiome (BGM) interactions have been implicated in the pathogenesis of irritable bowel syndrome (IBS). Here, we apply a systems biology approach, leveraging neuroimaging and fecal metabolite data, to characterize BGM interactions that are driving IBS pathophysiology. Feca...

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Veröffentlicht in:Transl Psychiatry
Hauptverfasser: Osadchiy, Vadim, Mayer, Emeran A., Gao, Kan, Labus, Jennifer S., Naliboff, Bruce, Tillisch, Kirsten, Chang, Lin, Jacobs, Jonathan P., Hsiao, Elaine Y., Gupta, Arpana
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7608552/
https://ncbi.nlm.nih.gov/pubmed/33139708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41398-020-01071-2
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