Analysis of brain networks and fecal metabolites reveals brain–gut alterations in premenopausal females with irritable bowel syndrome

Alterations in brain–gut–microbiome (BGM) interactions have been implicated in the pathogenesis of irritable bowel syndrome (IBS). Here, we apply a systems biology approach, leveraging neuroimaging and fecal metabolite data, to characterize BGM interactions that are driving IBS pathophysiology. Feca...

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Pubblicato in:Transl Psychiatry
Autori principali: Osadchiy, Vadim, Mayer, Emeran A., Gao, Kan, Labus, Jennifer S., Naliboff, Bruce, Tillisch, Kirsten, Chang, Lin, Jacobs, Jonathan P., Hsiao, Elaine Y., Gupta, Arpana
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7608552/
https://ncbi.nlm.nih.gov/pubmed/33139708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41398-020-01071-2
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