Human adipose mesenchymal stem cells modulate myeloid cells toward an anti-inflammatory and reparative phenotype: role of IL-6 and PGE2

BACKGROUND: Mesenchymal stem cells (MSCs) activate the endogenous immune regulatory system, inducing a therapeutic effect in recipients. MSCs have demonstrated the ability to modulate the differentiation of myeloid cells toward a phagocytic and anti-inflammatory profile. Allogeneic, adipose-derived...

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Publicat a:Stem Cell Res Ther
Autors principals: Ortiz-Virumbrales, Maitane, Menta, Ramón, Pérez, Laura M., Lucchesi, Ornella, Mancheño-Corvo, Pablo, Avivar-Valderas, Álvaro, Palacios, Itziar, Herrero-Mendez, Angel, Dalemans, Wilfried, de la Rosa, Olga, Lombardo, Eleuterio
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2020
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7607855/
https://ncbi.nlm.nih.gov/pubmed/33138862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-020-01975-2
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