Dissecting Allo-Sensitization After Local Administration of Human Allogeneic Adipose Mesenchymal Stem Cells in Perianal Fistulas of Crohn's Disease Patients

Adipose mesenchymal stem cells (ASC) are considered minimally immunogenic. This is due to the low expression of human leukocyte antigens I (HLA-I), lack of HLA-II expression and low expression of co-stimulatory molecules such as CD40 and CD80. The low rate of observed immunological rejection as well...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Avivar-Valderas, Alvaro, Martín-Martín, Cristina, Ramírez, Cristina, Del Río, Borja, Menta, Ramón, Mancheño-Corvo, Pablo, Ortiz-Virumbrales, Maitane, Herrero-Méndez, Ángel, Panés, Julián, García-Olmo, Damián, Castañer, José Luís, Palacios, Itziar, Lombardo, Eleuterio, Dalemans, Wilfried, DelaRosa, Olga
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6587893/
https://ncbi.nlm.nih.gov/pubmed/31258526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.01244
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