Enhanced production of taxadiene in Saccharomyces cerevisiae

BACKGROUND: Cost-effective production of the highly effective anti-cancer drug, paclitaxel (Taxol(®)), remains limited despite growing global demands. Low yields of the critical taxadiene precursor remains a key bottleneck in microbial production. In this study, the key challenge of poor taxadiene s...

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Detalhes bibliográficos
Publicado no:Microb Cell Fact
Main Authors: Nowrouzi, Behnaz, Li, Rachel A., Walls, Laura E., d’Espaux, Leo, Malcı, Koray, Liang, Lungang, Jonguitud-Borrego, Nestor, Lerma-Escalera, Albert I., Morones-Ramirez, Jose R., Keasling, Jay D., Rios-Solis, Leonardo
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7607689/
https://ncbi.nlm.nih.gov/pubmed/33138820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12934-020-01458-2
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