miRNA-126-3p carried by human umbilical cord mesenchymal stem cell enhances endothelial function through exosome-mediated mechanisms in vitro and attenuates vein graft neointimal formation in vivo

BACKGROUND: The aim of this study was to determine whether the combination of MSC implantation with miRNA-126-3p overexpression would further improve the surgical results after vein grafting. METHODS: human umbilical cord MSCs (hucMSCs) and human umbilical vein endothelial cells (HUVECs) were isolat...

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Bibliografski detalji
Izdano u:Stem Cell Res Ther
Glavni autori: Qu, Qingxi, Wang, Limei, Bing, Weidong, Bi, Yanwen, Zhang, Chunmei, Jing, Xuanxuan, Liu, Linghong
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2020
Teme:
Research
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7607661/
https://ncbi.nlm.nih.gov/pubmed/33138861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-020-01978-z
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