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Upregulation of miR-126-3p promotes human saphenous vein endothelial cell proliferation in vitro and prevents vein graft neointimal formation ex vivo and in vivo

Poor long-term patency of vein grafts remains an obstacle in coronary artery bypass grafting (CABG) surgery using an autologous saphenous vein graft. Recent studies have revealed that miR-126-3p promotes vascular integrity and angiogenesis. We aimed to identify the role of miR-126-3p in the setting...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Oncotarget
Hauptverfasser: Qu, Qingxi, Bing, Weidong, Meng, Xiangbin, Xi, Jie, Bai, Xiao, Liu, Qing, Guo, Yaqiu, Zhao, Xin, Bi, Yanwen
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5739774/
https://ncbi.nlm.nih.gov/pubmed/29290989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.22365
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