DNA methylation profiling distinguishes Ewing-like sarcoma with EWSR1-NFATc2 fusion from Ewing sarcoma

PURPOSE: Recent studies revealed divergent gene expression patterns in Ewing sarcoma (EwS) with canonical EWSR1-ETS gene fusions and undifferentiated round cell sarcomas (URCS) with EWSR1 rearrangements fused to the non-ETS gene NFATc2. Thus, the question arises whether the latter tumors really belo...

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Publicat a:J Cancer Res Clin Oncol
Autors principals: Koelsche, Christian, Kriegsmann, Mark, Kommoss, Felix K.F., Stichel, Damian, Kriegsmann, Katharina, Vokuhl, Christian, Grünewald, Thomas G.P., Romero-Pérez, Laura, Kirchner, Thomas, de Alava, Enrique, Diaz-Martin, Juan, Hartmann, Wolfgang, Baumhoer, Daniel, Antonescu, Cristina R., Szuhai, Karoly, Flucke, Uta, Dirksen, Uta, Pfister, Stefan M., Jones, David T.W., Mechtersheimer, Gunhild, von Deimling, Andreas
Format: Artigo
Idioma:Inglês
Publicat: 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7607515/
https://ncbi.nlm.nih.gov/pubmed/30895378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00432-019-02895-2
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