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Autoantigen Tetramer Silences Autoreactive B Cell Populations

Many autoimmune therapies focus on immune suppression to reduce symptom severity and halt disease progression; however, currently approved treatments lack specificity for the autoantigen and rely on more global immune suppression. Multivalent antigen arrays can disarm pathogenic autoimmune B cell po...

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Publicat a:Mol Pharm
Autors principals: Christopher, Matthew A., Johnson, Stephanie N., Griffin, J. Daniel, Berkland, Cory
Format: Artigo
Idioma:Inglês
Publicat: 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7606775/
https://ncbi.nlm.nih.gov/pubmed/32903002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.molpharmaceut.0c00665
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