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Correlative studies investigating effects of PI3K inhibition on peripheral leukocytes in metastatic breast cancer: potential implications for immunotherapy

PURPOSE: Patients with localized breast cancer have a 5-year survival rate >99% compared to patients with metastatic breast cancer (MBC) that have a 5-year survival rate of ~27%. Unregulated PI3K/AKT signaling is a common characteristic of MBC, making it a desirable therapeutic target for tumors...

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Detalhes bibliográficos
Publicado no:Breast Cancer Res Treat
Main Authors: Williams, Carly Bess, Nebhan, Caroline, Yang, Jinming, Starnes, Lauren S., Yan, Chi, Vilgelm, Anna E., Chen, Sheau-Chiann, Ayers, Gregory Dan, Abramson, Vandana, Mayer, Ingrid A., Richmond, Ann
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7606736/
https://ncbi.nlm.nih.gov/pubmed/32767201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-020-05846-5
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