Regulation of the thrombin/protease-activated receptor 1 axis by chemokine (CXC motif) receptor 4

The chemokine receptor CXCR4, a G protein–coupled receptor (GPCR) capable of heteromerizing with other GPCRs, is involved in many processes, including immune responses, hematopoiesis, and organogenesis. Evidence suggests that CXCR4 activation reduces thrombin/protease-activated receptor 1 (PAR1)-ind...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Gao, Xianlong, Cheng, You-Hong, Enten, Garrett A., DeSantis, Anthony J., Gaponenko, Vadim, Majetschak, Matthias
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2020
Assuntos:
Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7606691/
https://ncbi.nlm.nih.gov/pubmed/32839271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.015355
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