Integrated Single-Cell Atlases Reveal an Oral SARS-CoV-2 Infection and Transmission Axis

Despite signs of infection, the involvement of the oral cavity in COVID-19 is poorly understood. To address this, single-cell RNA sequencing data-sets were integrated from human minor salivary glands and gingiva to identify 11 epithelial, 7 mesenchymal, and 15 immune cell clusters. Analysis of SARS-...

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Publicado no:medRxiv
Main Authors: Huang, Ni, Perez, Paola, Kato, Takafumi, Mikami, Yu, Okuda, Kenichi, Gilmore, Rodney C., Domínguez Conde, Cecilia, Gasmi, Billel, Stein, Sydney, Beach, Margaret, Pelayo, Eileen, Maldonado, Jose, LaFont, Bernard, Padilla, Ricardo, Murrah, Valerie, Maile, Robert, Lovell, Will, Wallet, Shannon, Bowman, Natalie M., Meinig, Suzanne L, Wolfgang, Matthew C, Choudhury, Saibyasachi N., Novotny, Mark, Aevermann, Brian D, Scheuermann, Richard, Cannon, Gabrielle, Anderson, Carlton, Marchesan, Julie, Bush, Mandy, Freire, Marcelo, Kimple, Adam, Herr, Daniel L., Rabin, Joseph, Grazioli, Alison, French, Benjamin N., Pranzatelli, Thomas, Chiorini, John A., Kleiner, David E., Pittaluga, Stefania, Hewitt, Stephen, Burbelo, Peter D., Chertow, Daniel, Frank, Karen, Lee, Janice, Boucher, Richard C., Teichmann, Sarah A., Warner, Blake M., Byrd, Kevin M.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7605572/
https://ncbi.nlm.nih.gov/pubmed/33140061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2020.10.26.20219089
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