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Liver epithelial focal adhesion kinase modulates fibrogenesis and hedgehog signaling
Focal adhesion kinase (FAK) is an important mediator of extracellular matrix–integrin mechano-signal transduction that regulates cell motility, survival, and proliferation. As such, FAK is being investigated as a potential therapeutic target for malignant and fibrotic diseases, and numerous clinical...
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| Veröffentlicht in: | JCI Insight |
|---|---|
| Hauptverfasser: | , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Clinical Investigation
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7605528/ https://ncbi.nlm.nih.gov/pubmed/32910808 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.141217 |
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