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NfL as a biomarker for neurodegeneration and survival in Parkinson disease

OBJECTIVE: To determine whether neurofilament light chain protein in CSF (cNfL), a sensitive biomarker of neuroaxonal damage, reflects disease severity or can predict survival in Parkinson disease (PD). METHODS: We investigated whether disease severity, phenotype, or survival in patients with new-on...

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Detalhes bibliográficos
Publicado no:Neurology
Main Authors: Bäckström, David, Linder, Jan, Jakobson Mo, Susanna, Riklund, Katrine, Zetterberg, Henrik, Blennow, Kaj, Forsgren, Lars, Lenfeldt, Niklas
Formato: Artigo
Idioma:Inglês
Publicado em: Lippincott Williams & Wilkins 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7605503/
https://ncbi.nlm.nih.gov/pubmed/32680941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0000000000010084
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