Evaluating plasma biomarkers NfL, GFAP, GDF15, and FGF21 as indicators of disease severity in Charcot–Marie Tooth patients

BackgroundCharcot–Marie–Tooth disease (CMT), a slowly advancing hereditary nerve disorder, presents a significant challenge in the medical field. Effective drugs for treatment are lacking, and we struggle to find sensitive markers to track the disease’s severity and progression. In this study, our o...

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Autores principales:	Dace Pretkalnina, Elizabete Kenina, Linda Gailite, Dmitrijs Rots, Kaj Blennow, Henrik Zetterberg, Viktorija Kenina
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Frontiers Media S.A. 2025-01-01
Colección:	Frontiers in Neurology
Materias:	CMT biomarker NFL FGF21 GFAP - glial fibrillary acidic protein GDF15
Acceso en línea:	https://www.frontiersin.org/articles/10.3389/fneur.2024.1490024/full
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