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TRPV4 calcium influx controls sclerostin protein loss independent of purinergic calcium oscillations
Skeletal remodeling is driven in part by the osteocyte’s ability to respond to its mechanical environment by regulating the abundance of sclerostin, a negative regulator of bone mass. We have recently shown that the osteocyte responds to fluid shear stress via the microtubule network-dependent activ...
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| Publicado no: | Bone |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7605285/ https://ncbi.nlm.nih.gov/pubmed/32272228 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2020.115356 |
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