Genome-wide dynamics of RNA synthesis, processing, and degradation without RNA metabolic labeling

The quantification of the kinetic rates of RNA synthesis, processing, and degradation are largely based on the integrative analysis of total and nascent transcription, the latter being quantified through RNA metabolic labeling. We developed INSPEcT−, a computational method based on the mathematical...

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Vydáno v:Genome Res
Hlavní autoři: Furlan, Mattia, Galeota, Eugenia, Gaudio, Nunzio Del, Dassi, Erik, Caselle, Michele, de Pretis, Stefano, Pelizzola, Mattia
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2020
Témata:
Method
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7605262/
https://ncbi.nlm.nih.gov/pubmed/32978246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.260984.120
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