Genome-wide dynamics of RNA synthesis, processing, and degradation without RNA metabolic labeling

The quantification of the kinetic rates of RNA synthesis, processing, and degradation are largely based on the integrative analysis of total and nascent transcription, the latter being quantified through RNA metabolic labeling. We developed INSPEcT−, a computational method based on the mathematical...

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Publicat a:Genome Res
Autors principals: Furlan, Mattia, Galeota, Eugenia, Gaudio, Nunzio Del, Dassi, Erik, Caselle, Michele, de Pretis, Stefano, Pelizzola, Mattia
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2020
Matèries:
Method
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7605262/
https://ncbi.nlm.nih.gov/pubmed/32978246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.260984.120
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