Φορτώνει......
Comparative intracerebroventricular (ICV) and intrathecal (IT) administration of a nanomolar macrocyclic melanocortin receptor agonist MDE6-5-2c (c[Pro-His-DPhe-Arg-Trp-Dap-Ala-DPro]) decreases food intake in mice.
There is a critical need to find safe therapeutics to treat an increasingly obese population and diseases associated with an imbalance in energy homeostasis. The melanocortin-3 receptor (MC3R) and melanocortin-4 receptor (MC4R) ligands have long been the focus to help scientists understand energy ho...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | ACS Chem Neurosci |
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| Κύριοι συγγραφείς: | , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2020
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7605118/ https://ncbi.nlm.nih.gov/pubmed/32822157 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschemneuro.0c00409 |
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