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Synthesis and Antiviral Properties of 1-Substituted 3-[ω-(4-Oxoquinazolin-4(3H)-yl)alkyl]uracil Derivatives

A series of uracil derivatives containing a 4-oxoquinazoline fragment bound to the nitrogen atom N3 of the pyrimidine ring by a short methylene bridge was synthesized to search for new antiviral agents. Some compounds in this series are shown to exhibit high inhibitory activity against human cytomeg...

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Detalhes bibliográficos
Publicado no:Acta Naturae
Main Authors: Paramonova, M. P., Khandazhinskaya, A. L., Ozerov, A. A., Kochetkov, S. N., Snoeck, R., Andrei, G., Novikov, M. S.
Formato: Artigo
Idioma:Inglês
Publicado em: A.I. Gordeyev 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7604896/
https://ncbi.nlm.nih.gov/pubmed/33173603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.32607/actanaturae.10983
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