Overexpression of RNF126 Promotes the Development of Colorectal Cancer via Enhancing p53 Ubiquitination and Degradation

BACKGROUND: RING finger protein 126 (RNF126), as a novel E3 ubiquitin ligase, plays an oncogenic role in several solid cancers. But its potential role in colorectal cancer (CRC) that harbored 50% mutant p53, to our knowledge, is rarely reported. MATERIALS AND METHODS: We investigated the clinical si...

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Bibliografiska uppgifter
I publikationen:Onco Targets Ther
Huvudupphovsmän: Wang, Shiyang, Wang, Tianlong, Wang, Li, Zhong, Liansheng, Li, Kai
Materialtyp: Artigo
Språk:Inglês
Publicerad: Dove 2020
Ämnen:
Original Research
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7604871/
https://ncbi.nlm.nih.gov/pubmed/33149608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S271855
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