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Overexpression of RNF126 Promotes the Development of Colorectal Cancer via Enhancing p53 Ubiquitination and Degradation
BACKGROUND: RING finger protein 126 (RNF126), as a novel E3 ubiquitin ligase, plays an oncogenic role in several solid cancers. But its potential role in colorectal cancer (CRC) that harbored 50% mutant p53, to our knowledge, is rarely reported. MATERIALS AND METHODS: We investigated the clinical si...
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| Publicado no: | Onco Targets Ther |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Dove
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7604871/ https://ncbi.nlm.nih.gov/pubmed/33149608 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S271855 |
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