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β-Carotene conversion to vitamin A delays atherosclerosis progression by decreasing hepatic lipid secretion in mice

Atherosclerosis is characterized by the pathological accumulation of cholesterol-laden macrophages in the arterial wall. Atherosclerosis is also the main underlying cause of CVDs, and its development is largely driven by elevated plasma cholesterol. Strong epidemiological data find an inverse associ...

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Detalhes bibliográficos
Publicado no:J Lipid Res
Main Authors: Zhou, Felix, Wu, Xiaoyun, Pinos, Ivan, Abraham, Benjamin M., Barrett, Tessa J., von Lintig, Johannes, Fisher, Edward A., Amengual, Jaume
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7604725/
https://ncbi.nlm.nih.gov/pubmed/32963037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.RA120001066
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