Dietary 9-cis-β,β-Carotene Fails to Rescue Vision in Mouse Models of Leber Congenital Amaurosis

Synthetic 9-cis-stereoisomers of vitamin A (all-trans-retinol) are especially promising agents for the fight against blinding diseases. Several studies suggested that 9-cis-β,β-carotene (9-cis-BC), a natural and abundant β-carotene isomer in the diet, could be the precursor of 9-cis-retinoids and th...

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Bibliografiska uppgifter
Huvudupphovsmän: Maeda, Tadao, Perusek, Lindsay, Amengual, Jaume, Babino, Darwin, Palczewski, Krzysztof, von Lintig, Johannes
Materialtyp: Artigo
Språk:Inglês
Publicerad: The American Society for Pharmacology and Experimental Therapeutics 2011
Ämnen:
Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3198919/
https://ncbi.nlm.nih.gov/pubmed/21862692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.111.074732
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