Leukemia cells remodel marrow adipocytes via TRPV4-dependent lipolysis

Remodeling of adipocyte morphology and function plays a critical role in prostate cancer development. We previously reported that leukemia cells secrete growth differentiation factor 15 (GDF15), which remodels the residual bone marrow (BM) adipocytes into small adipocytes and is associated with a po...

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Pubblicato in:Haematologica
Autori principali: Yang, Shaoxin, Lu, Wei, Zhao, Chong, Zhai, Yuanmei, Wei, Yanyu, Liu, Jiali, Yu, Yehua, Li, Zhiqiang, Shi, Jun
Natura: Artigo
Lingua:Inglês
Pubblicazione: Fondazione Ferrata Storti 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7604636/
https://ncbi.nlm.nih.gov/pubmed/33131246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2019.225763
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