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Leukemia cells remodel marrow adipocytes via TRPV4-dependent lipolysis

Remodeling of adipocyte morphology and function plays a critical role in prostate cancer development. We previously reported that leukemia cells secrete growth differentiation factor 15 (GDF15), which remodels the residual bone marrow (BM) adipocytes into small adipocytes and is associated with a po...

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Detalhes bibliográficos
Publicado no:Haematologica
Main Authors: Yang, Shaoxin, Lu, Wei, Zhao, Chong, Zhai, Yuanmei, Wei, Yanyu, Liu, Jiali, Yu, Yehua, Li, Zhiqiang, Shi, Jun
Formato: Artigo
Idioma:Inglês
Publicado em: Fondazione Ferrata Storti 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7604636/
https://ncbi.nlm.nih.gov/pubmed/33131246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2019.225763
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