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Leukemia cells remodel marrow adipocytes via TRPV4-dependent lipolysis

Remodeling of adipocyte morphology and function plays a critical role in prostate cancer development. We previously reported that leukemia cells secrete growth differentiation factor 15 (GDF15), which remodels the residual bone marrow (BM) adipocytes into small adipocytes and is associated with a po...

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Bibliografiske detaljer
Udgivet i:Haematologica
Main Authors: Yang, Shaoxin, Lu, Wei, Zhao, Chong, Zhai, Yuanmei, Wei, Yanyu, Liu, Jiali, Yu, Yehua, Li, Zhiqiang, Shi, Jun
Format: Artigo
Sprog:Inglês
Udgivet: Fondazione Ferrata Storti 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7604636/
https://ncbi.nlm.nih.gov/pubmed/33131246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2019.225763
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