Migfilin supports hemostasis and thrombosis through regulating platelet aIIbβ3 outside-in signaling

Elucidating the regulation mechanism of integrin aIIbβ3 is key to understanding platelet biology and thrombotic diseases. Previous in vitro studies have implicated a role of migfilin in the support of platelet aIIbβ3 activation, however, contribution of migfilin to thrombosis and hemostasis in vivo...

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Bibliographic Details
Published in:Haematologica
Main Authors: Zhou, Yangfan, Hu, Mengjiao, Chen, Xiaoyan, Wang, Shuai, Li, Jingke, Sa, Lina, Li, Li, Huang, Jiaqi, Cheng, Hongqiang, Hu, Hu
Format: Artigo
Language:Inglês
Published: Fondazione Ferrata Storti 2019
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7604612/
https://ncbi.nlm.nih.gov/pubmed/33131250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2019.232488
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