Clinical outcomes and characteristics of patients with TP53-mutated acute myeloid leukemia or myelodysplastic syndromes: A single center experience

Mutations in the tumor suppressor gene TP53 are detected in 5–10% of patients with acute myeloid leukemia (AML) and myelodysplastic syndromes. TP53 mutations have been associated with complex karyotypes, therapy-related malignancies, lower response rates to cytotoxic chemotherapy, and an overall adv...

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Bibliografiske detaljer
Udgivet i:Leuk Lymphoma
Main Authors: Bewersdorf, Jan Philipp, Shallis, Rory M., Gowda, Lohith, Wei, Wei, Hager, Karl, Isufi, Iris, Kim, Tae Kon, Pillai, Manoj M., Seropian, Stuart, Podoltsev, Nikolai A., Gore, Steven D., Siddon, Alexa J., Zeidan, Amer M.
Format: Artigo
Sprog:Inglês
Udgivet: 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7603787/
https://ncbi.nlm.nih.gov/pubmed/32362171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10428194.2020.1759051
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