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Characterization of WWOX expression and function in canine mast cell tumors and malignant mast cell lines

BACKGROUND: The WW domain-containing oxidoreductase (WWOX) tumor suppressor gene is frequently lost in a variety of solid and hematopoietic malignancies in humans. Dysregulation of WWOX has been implicated as playing a key role in tumor cell survival, DNA damage repair, and genomic stability. The pu...

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Detalhes bibliográficos
Publicado no:BMC Vet Res
Main Authors: Makii, Rebecca, Cook, Hanna, Louke, Darian, Breitbach, Justin, Jennings, Ryan, Premanandan, Christopher, Green, Eric M., Fenger, Joelle M.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7603737/
https://ncbi.nlm.nih.gov/pubmed/33129329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12917-020-02638-3
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