MUTYH Deficiency Is Associated with Attenuated Pulmonary Fibrosis in a Bleomycin-Induced Model

Idiopathic pulmonary fibrosis (IPF) is a progressive, irreversible lung disease of unknown etiology with limited survival. IPF incidence and prevalence increase significantly with aging, which is associated with an age-related accumulation of oxidative DNA damage. The Mutyh gene is involved in the b...

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Publicado en:Oxid Med Cell Longev
Autores principales: Sun, Qingmin, Chen, Jingwen, Xu, Lizhi, Kang, Jiaqi, Wu, Xin, Ren, Yan, Nakabeppu, Yusaku, Wang, Yaping
Formato: Artigo
Lenguaje:Inglês
Publicado: Hindawi 2020
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7603627/
https://ncbi.nlm.nih.gov/pubmed/33149810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/4828256
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