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In vitro biotransformation of pyrrolizidine alkaloids in different species: part II—identification and quantitative assessment of the metabolite profile of six structurally different pyrrolizidine alkaloids

Pyrrolizidine alkaloids (PA) exert their toxic effects only after bioactivation. Although their toxicity has already been studied and metabolic pathways including important metabolites were described, the quantification of the latter revealed a large unknown portion of the metabolized PA. In this st...

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Bibliografiska uppgifter
I publikationen:Arch Toxicol
Huvudupphovsmän: Geburek, Ina, Schrenk, Dieter, These, Anja
Materialtyp: Artigo
Språk:Inglês
Publicerad: Springer Berlin Heidelberg 2020
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7603446/
https://ncbi.nlm.nih.gov/pubmed/32880719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00204-020-02853-9
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