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In vitro biotransformation of pyrrolizidine alkaloids in different species. Part I: Microsomal degradation

Pyrrolizidine alkaloids (PA) are secondary metabolites of certain flowering plants. The ingestion of PAs may result in acute and chronic effects in man and livestock with hepatotoxicity, mutagenicity, and carcinogenicity being identified as predominant effects. Several hundred PAs sharing the diol p...

詳細記述

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書誌詳細
出版年:Arch Toxicol
主要な著者: Kolrep, Franziska, Numata, Jorge, Kneuer, Carsten, Preiss-Weigert, Angelika, Lahrssen-Wiederholt, Monika, Schrenk, Dieter, These, Anja
フォーマット: Artigo
言語:Inglês
出版事項: Springer Berlin Heidelberg 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5866832/
https://ncbi.nlm.nih.gov/pubmed/29143854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00204-017-2114-7
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