Metformin Reduces NGF-Induced Tumour Promoter Effects in Epithelial Ovarian Cancer Cells

Epithelial ovarian cancer (EOC) is a lethal gynaecological neoplasm characterized by rapid growth and angiogenesis. Nerve growth factor (NGF) and its high affinity receptor tropomyosin receptor kinase A (TRKA) contribute to EOC progression by increasing the expression of c-MYC, survivin and vascular...

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Detalhes bibliográficos
Publicado no:Pharmaceuticals (Basel)
Main Authors: Garrido, Maritza P., Salvatierra, Renato, Valenzuela-Valderrama, Manuel, Vallejos, Christopher, Bruneau, Nicole, Hernández, Andrea, Vega, Margarita, Selman, Alberto, Quest, Andrew F. G., Romero, Carmen
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7602813/
https://ncbi.nlm.nih.gov/pubmed/33081077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph13100315
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