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NGF-Enhanced Vasculogenic Properties of Epithelial Ovarian Cancer Cells Is Reduced by Inhibition of the COX-2/PGE(2) Signaling Axis

Epithelial ovarian cancer (EOC) is a lethal gynecological neoplasia characterized by extensive angiogenesis and overexpression of nerve growth factor (NGF). Here, we investigated the mechanism by which NGF increases vascular endothelial growth factor (VEGF) expression and the vasculogenic potential...

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Detalles Bibliográficos
Publicado en:Cancers (Basel)
Main Authors: Garrido, Maritza P., Hurtado, Iván, Valenzuela-Valderrama, Manuel, Salvatierra, Renato, Hernández, Andrea, Vega, Margarita, Selman, Alberto, Quest, Andrew F. G., Romero, Carmen
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6966471/
https://ncbi.nlm.nih.gov/pubmed/31817839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11121970
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