NGF-Enhanced Vasculogenic Properties of Epithelial Ovarian Cancer Cells Is Reduced by Inhibition of the COX-2/PGE(2) Signaling Axis

Epithelial ovarian cancer (EOC) is a lethal gynecological neoplasia characterized by extensive angiogenesis and overexpression of nerve growth factor (NGF). Here, we investigated the mechanism by which NGF increases vascular endothelial growth factor (VEGF) expression and the vasculogenic potential...

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Bibliografiske detaljer
Udgivet i:Cancers (Basel)
Main Authors: Garrido, Maritza P., Hurtado, Iván, Valenzuela-Valderrama, Manuel, Salvatierra, Renato, Hernández, Andrea, Vega, Margarita, Selman, Alberto, Quest, Andrew F. G., Romero, Carmen
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6966471/
https://ncbi.nlm.nih.gov/pubmed/31817839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11121970
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