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Arsenic Promotes the COX2/PGE2-SOX2 Axis to Increase the Malignant Stemness Properties of Urothelial Cells

Chronic arsenic exposure is associated with the development of urothelial carcinoma of the bladder (UCB). To elucidate the contribution of arsenic exposure to urothelial cancer stem cell (CSC) generation, we established an in vitro stepwise malignant model transformed by chronically exposing human u...

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Detalhes bibliográficos
Publicado no:Int J Cancer
Main Authors: Ooki, Akira, Begum, Asma, Marchionni, Luigi, VandenBussche, Christopher J., Mao, Shifeng, Kates, Max, Hoque, Mohammad Obaidul
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5938132/
https://ncbi.nlm.nih.gov/pubmed/29396848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.31290
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