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Arsenic Promotes the COX2/PGE2-SOX2 Axis to Increase the Malignant Stemness Properties of Urothelial Cells

Chronic arsenic exposure is associated with the development of urothelial carcinoma of the bladder (UCB). To elucidate the contribution of arsenic exposure to urothelial cancer stem cell (CSC) generation, we established an in vitro stepwise malignant model transformed by chronically exposing human u...

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Dades bibliogràfiques
Publicat a:Int J Cancer
Autors principals: Ooki, Akira, Begum, Asma, Marchionni, Luigi, VandenBussche, Christopher J., Mao, Shifeng, Kates, Max, Hoque, Mohammad Obaidul
Format: Artigo
Idioma:Inglês
Publicat: 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5938132/
https://ncbi.nlm.nih.gov/pubmed/29396848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.31290
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