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Targeting DNA Repair, Cell Cycle, and Tumor Microenvironment in B Cell Lymphoma
The DNA double-strand break (DSB) is the most cytotoxic lesion and compromises genome stability. In an attempt to efficiently repair DSBs, cells activate ATM kinase, which orchestrates the DNA damage response (DDR) by activating cell cycle checkpoints and initiating DSB repair pathways. In physiolog...
Guardat en:
| Publicat a: | Cells |
|---|---|
| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
MDPI
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7602196/ https://ncbi.nlm.nih.gov/pubmed/33066395 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9102287 |
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