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Targeting DNA Repair, Cell Cycle, and Tumor Microenvironment in B Cell Lymphoma

The DNA double-strand break (DSB) is the most cytotoxic lesion and compromises genome stability. In an attempt to efficiently repair DSBs, cells activate ATM kinase, which orchestrates the DNA damage response (DDR) by activating cell cycle checkpoints and initiating DSB repair pathways. In physiolog...

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Detalhes bibliográficos
Publicado no:Cells
Main Authors: Bröckelmann, Paul J., de Jong, Mathilde R. W., Jachimowicz, Ron D.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7602196/
https://ncbi.nlm.nih.gov/pubmed/33066395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9102287
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