Targeting and Efficacy of Novel mAb806-Antibody-Drug Conjugates in Malignant Mesothelioma

Epidermal growth factor receptor (EGFR) is highly overexpressed in malignant mesothelioma (MM). MAb806 is a novel anti-EGFR antibody that selectively targets a tumor-selective epitope. MAb806-derived antibody drug conjugates (ADCs), ABT-414, ABBV-221 and ABBV-322, may represent a novel therapeutic s...

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Détails bibliographiques
Publié dans:Pharmaceuticals (Basel)
Auteurs principaux: Chia, Puey-Ling, Parakh, Sagun, Tsao, Ming-Sound, Pham, Nhu-An, Gan, Hui K., Cao, Diana, Burvenich, Ingrid J. G., Rigopoulos, Angela, Reilly, Edward B., John, Thomas, Scott, Andrew M.
Format: Artigo
Langue:Inglês
Publié: MDPI 2020
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7601847/
https://ncbi.nlm.nih.gov/pubmed/33023139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph13100289
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