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Premature Vascular Aging with Features of Plaque Vulnerability in an Atheroprone Mouse Model of Hutchinson–Gilford Progeria Syndrome with Ldlr Deficiency

Hutchinson–Gilford progeria syndrome (HGPS) is among the most devastating of the laminopathies, rare genetic diseases caused by mutations in genes encoding nuclear lamina proteins. HGPS patients age prematurely and die in adolescence, typically of atherosclerosis-associated complications. The mechan...

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Bibliografische gegevens
Gepubliceerd in:Cells
Hoofdauteurs: Nevado, Rosa M., Hamczyk, Magda R., Gonzalo, Pilar, Andrés-Manzano, María Jesús, Andrés, Vicente
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI 2020
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7601818/
https://ncbi.nlm.nih.gov/pubmed/33049978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9102252
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