Premature Vascular Aging with Features of Plaque Vulnerability in an Atheroprone Mouse Model of Hutchinson–Gilford Progeria Syndrome with Ldlr Deficiency

Hutchinson–Gilford progeria syndrome (HGPS) is among the most devastating of the laminopathies, rare genetic diseases caused by mutations in genes encoding nuclear lamina proteins. HGPS patients age prematurely and die in adolescence, typically of atherosclerosis-associated complications. The mechan...

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Vydáno v:Cells
Hlavní autoři: Nevado, Rosa M., Hamczyk, Magda R., Gonzalo, Pilar, Andrés-Manzano, María Jesús, Andrés, Vicente
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7601818/
https://ncbi.nlm.nih.gov/pubmed/33049978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9102252
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