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UCH-L1 inhibitor LDN-57444 hampers mouse oocyte maturation by regulating oxidative stress and mitochondrial function and reducing ERK1/2 expression

Oocyte maturation is a prerequisite for successful fertilization and embryo development. Incomplete oocyte maturation can result in infertility. Ubiquitin carboxy-terminal hydrolase L1 (UCH-L1) has been found to be implicated in oocyte maturation and embryo development. However, the cellular and mol...

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Bibliografiske detaljer
Udgivet i:Biosci Rep
Main Authors: Yuan, Pan, Zhou, Li, Zhang, Xiaona, Yao, Lan, Ning, Jun, Han, Xiao, Ming, Caifeng, Zhao, Yunhe, Zhang, Liqun
Format: Artigo
Sprog:Inglês
Udgivet: Portland Press Ltd. 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7601359/
https://ncbi.nlm.nih.gov/pubmed/33030206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20201308
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