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Senescent Tumor CD8(+) T Cells: Mechanisms of Induction and Challenges to Immunotherapy

SIMPLE SUMMARY: Immunotherapies harness the hosts’ immune system to combat cancer and are currently used to treat many tumor types. Immunotherapies mainly target T cells, the major immune population responsible for tumor-cell killing. One of the reasons that T cells may not respond to immunotherapeu...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Liu, Wei, Stachura, Paweł, Xu, Haifeng C., Bhatia, Sanil, Borkhardt, Arndt, Lang, Philipp A., Pandyra, Aleksandra A.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7601312/
https://ncbi.nlm.nih.gov/pubmed/33008037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12102828
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