Assessment of CAR T Cell Frequencies in Axicabtagene Ciloleucel and Tisagenlecleucel Patients Using Duplex Quantitative PCR

SIMPLE SUMMARY: To monitor patients after CAR T cell treatment, measuring frequencies of chimeric antigen receptor (CAR) T cells is crucial. However, experimental assays to quantify CAR T cells are lacking. Here, we describe a quantitative single copy gene-based PCR approach to measure frequencies o...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Schubert, Maria-Luisa, Kunz, Alexander, Schmitt, Anita, Neuber, Brigitte, Wang, Lei, Hückelhoven-Krauss, Angela, Langner, Sascha, Michels, Birgit, Wick, Antje, Daniel, Volker, Müller-Tidow, Carsten, Dreger, Peter, Schmitt, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Brief Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7601213/
https://ncbi.nlm.nih.gov/pubmed/33007926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12102820
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